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Gestational Diabetes (During Pregnancy)



Definition:

Gestational diabetes is a type of diabetes that starts during pregnancy. If the pregnant woman has diabetes, her body is not able to use the sugar (glucose) in her blood as well as it should. So the level of sugar in her blood becomes higher than normal. Gestational diabetes affects about 4% of all pregnant women ,it usually begins in the fifth or sixth month of pregnancy (Between the 24th and 28th weeks). Most often, gestational diabetes goes away after the baby is born.

Causes of gestational diabetes:

Almost all women have some degree of impaired glucose intolerance during pregnancy because of hormonal changes that occur during pregnancy. That means that their blood sugar may be higher than normal, but not high enough to have diabetes. During the later part of pregnancy (the third trimester) these hormonal changes place pregnant women at risk for gestational diabetes.
During pregnancy, increased levels of certain hormones made in the placenta (the organ that connects the baby by the umbilical cord to the uterus) help shift nutrients from the mother to the developing fetus. Other hormones are produced by the placenta to help prevent the mother from developing low blood sugar. They work by stopping the actions of insulin.
Over the course of the pregnancy, these hormones lead to progressive impaired glucose intolerance, which leads to higher blood glucose level. To try to decrease the glucose levels. The body makes more insulin to shuttle glucose into cells.
Usually the mother's pancreas is able to produce more insulin (about three times the normal amount) to overcome the effect of the pregnancy hormones on glucose levels. If, however, the pancreas cannot produce enough insulin to overcome the effect of the increased hormones during pregnancy glucose levels will rise, resulting in gestational diabetes.

Risk factors:

The following factors increase the risk of developing diabetes during pregnancy:

1. being overweight prior to becoming pregnant.

2. Having glucose in the urine.

3. Impaired glucose tolerance or impaired fasting glucose (blood glucose levels are high, but not high enough to be diabetic.)

4. Family history of diabetes. (If the parents or siblings have diabetes)

5. Previously giving birth to a baby over 9 pounds.

6. Previously giving birth to a stillborn baby.

7. Having gestational diabetes with a previous pregnancy.

8. Having too much amniotic fluid (A condition called polyhydramnios)

*Many women who develop gestational diabetes have no known risk factors.

Symptoms:

Usually there are no symptoms, but the following may be occur:

1. Increased thirst
2. Increased urination
3. Weight loss in spite of increased appetite
4. Fatigue
5. Nausea and vomiting
6. Frequent infections including those of the bladder vagina and skin
7. Blurred vision

Note. Although these symptoms are also common later in pregnancy anyway.

Diagnosis:

High-risk women should be screened for gestational diabetes as early as possible during their pregnancies, all other women will be screened between the 24th and 28th week of pregnancy.
To screen for gestational diabetes, the pregnant woman will take a test called the oral glucose tolerance test. This test involves quickly drinking a sweetened liquid, which contains 50g of glucose. The body absorbs this glucose rapidly, causing blood glucose level to rise within 30-60 min. a blood sample will be taken from a vein in your arm 1 hour after drinking the solution. The blood test measures how the glucose solution was metabolized (processed by the body) blood glucose greater than or equal to 140 mg/dl is recognized as abnormal. If the results are abnormal based on the oral glucose tolerance test, another test will be given after fasting several hours.
In women at high risk of developing gestational diabetes, a normal screening test result is followed up with another screening test at 24-42 weeks for confirmation of the diagnosis.


Treatment:

The goals of treatments are to maintain blood glucose level within normal limits during the duration of the pregnancy, and ensure the well-being of the fetus.

1. Close monitoring of the mother and the fetus should continue throughout the pregnancy.
- Fetal monitoring to assess the fetal size and well-being may include ultrasound exams and non-stress tests. A non- stress test is a very simple painless test for the mother and her baby, an electronic fetal monitor (a machine that hears and displays the baby's heartbeat) is placed on the abdomen. When the baby moves, His heart rate normally increases 15 to 20 beats above its regular rate.
- Self-monitoring of blood glucose level allows the women to participate in her care. Monitoring blood glucose levels four times per day (before breakfast and 2 hours after meals monitoring blood glucose before all meals may also become necessary) the range include: before breakfast: plasma < 105 mg/dl, 2 hours after meals: plasma < 130 mg/dl

2. Following specific dietary guidelines as instructed by the doctor. The pregnant woman will be asked to distribute the calories evenly throughout the day. Follow these eating tips:
الغذاء
A. Eat three small meals and two or three snacks at regular time's everyday. Do not skip meals or snacks, carbohydrates should be 40% - 45% of the total calories with breakfast and a bedtime snack containing 15 – 30 grams of carbohydrates.
B. If the mother has morning sickness, she should eat 1-2 servings of crackers, cereal or pretzels before getting out of bed. Eat small, frequent meals throughout the day and avoid fatty, fried and greasy foods. If she takes insulin and has morning sickness, make sure how to treat low blood sugar.
C. Choose foods high in fiber such as whole-grain breads cereals, pasta, rice, fruits and vegetables. all pregnant women should eat 20 – 35 grams of fiber a day.
D. Fat should be less than 40% of calories with less than 10% consumed being from saturated fats
E. The pregnant woman should make sure that she is getting enough vitamins and minerals in her daily diet.
F. Drink at least 8 cups or 64 ounces of liquids per day.

3. Regular exercise during pregnancy can improve the posture and decrease some common discomforts such as backache and fatigue. Being fit during pregnancy means Safe, mild to moderate exercise at least three times a week. However, every pregnant woman should consult with her doctor before beginning an exercise programتمرينات أخرى للحوامل
Since both insulin and exercise lower blood glucose, the mother should follow additional exercise to avoid a low blood glucose reaction:
- Always carry any kind of sugar with her when exercising such as glucose tablets or hard candy.
- eat one serving of fruit or the equivalent of 15gm of carbohydrate for most activities lasting 30 min. if the pregnant woman exercises 2 hours or more after a meal, eat the snack before exercise.

4. Monitoring weight gain: The recommend amount of weight gained during pregnancy depends on the pre-pregnancy weight, whether there are more than one fetus and the trimester. Typically, more weight gain is expected during the second and third trimester and recommended intakes of calories should increase at that time.
Gaining the right amount of weight during pregnancy by eating a healthy, balanced diet is a good sign that the baby is getting all the nutrients he or she needs and is growing at a healthy rate.
It is not necessary to "eat for two" during pregnancy. It's true that pregnant woman needs extra calories from nutrient-rich foods to help her baby grow, but she generally need to consume 200 to 300 more calories than she did before she became pregnant to meet the needs of her growing baby. She must ask the doctor how much weight she should gain during pregnancy. A woman of average weight before pregnancy can expect to gain 25 to 35 pounds during pregnancy. She may need to gain more or less weight, depending on what her doctor recommends.
In general, the pregnant woman should gain about 24 pounds during first 3 months of pregnancy and 1 pound a week for the remainder of the pregnancy.

* Where the weight goes:

- Baby 8 pounds
- Placenta 2-3 pounds
- Amniotic fluid 2-3 pounds
- Breast tissue 2-3 pounds
- Blood supply 4 pounds
- Fat stores for delivery and breast-feeding 5-9 pounds
- Uterus increase 2-5 pounds

5- Medical Treatment

Based on the mother blood glucose monitoring results, the doctor will tell her if she needs to take insulin in the form of injections during pregnancy. Insulin is a hormone that controls blood glucose if insulin is prescribed for her, she may be taught to perform the insulin injection procedure.
As the pregnancy progresses, the placenta will make more pregnancy hormones and larger doses of insulin may be needed to control the mother's blood glucose. the doctor will adjust her insulin dosage based on her blood glucose level.
When using insulin, a "low blood glucose reaction", or hypoglycemia, can occur if the mother do not eat enough food, skip a meal, do not eat at the right time of day or if she exercises more than usual.

- Symptoms of hypoglycemia include:

* Confusion
* Dizziness
* feeling shaky
* Head aches
* Sudden hunger
* sweating
* Weakness

Hypoglycemia is a serious problem that needs to be treated right away. If the pregnant woman thinks that she has a low blood glucose reaction, she should check her blood glucose. If the blood glucose is less than 60 mg/dl, eat a sugar – containing food, such as 1/2 cup of orange or apple juice, 1 cup of skim milk, 4-6 pieces of hard candy (not sugar – free), 1/2 cup regular soft drink; or 1 tbsp of honey, brown sugar or corn syrup. 15 min after eating one of the foods listed above, check your blood glucose if it is still less than 60 mg/db, eat another one of the food choices above. If it is more than 45 min until the next meal, eat a bread and protein source to prevent another reaction. Record all low blood glucose reactions in the logbook, including the date, time of day the reaction occurred and how she treated it.

Complications:

Diabetes in pregnant women can affect the developing baby throughout the pregnancy:

A – In early pregnancy: maternal diabetes can result in

1. Birth defects affect major organs such as the brain and heart.
2. Increased rate of miscarriage.

B – During the 2nd and 3rd trimester:

1. Maternal diabetes can lead to over – nutrition and excess growth of the baby.
2. Having a large baby increases risks during labour and delivery.
3. Large babies often requires caesarean deliveries and if he or she is delivered vaginally, they are at increased risk trauma to their shoulder


C - After Birth:

1. The baby may have low blood sugar (hypoglycemia) after birth. This is because the baby's pancreas makes extra insulin in response to the mother's high blood sugar level. Shortly after birth, the baby may continue to make extra insulin even though high level of blood sugar is no longer present. After the pregnancy, the newborn blood sugar level is checked regularly. Sometimes babies are given an early feed of a sugar (glucose) solution through a drip (fed directly into a vein) to correct low blood sugar.

2. It is more likely that the newborn baby will develop jaundice (yellowing of the skin and whites of the eyes). This is not serious and usually fades over a few weeks, without the need for medical treatment.
3. There may be an increased risk of the baby developing type II diabetes or being overweight later in life.

4. There is an increase risk that the baby will be born with congenital problems, such as heart defect. Sometimes infants can be born with respiratory distress syndrome, in which the baby has problems breathing because his or her lungs have not matured as normal. This usually clears up with time.
5. There is also a slightly higher chance of stillbirth or death as a newborn, but if it is detected and the glucose level was managed, death is rare.

D - Effects on the mother

Gestational diabetes is not an immediate threat to the woman's health. Most women with gestational diabetes whose blood sugar levels stay within the safe range, Deliver their babies without complications. However, in some women it can result in high blood pressure. Women who get gestational diabetes are more likely to develop gestational diabetes in future pregnancies, and are at a higher risk of developing type II diabetes later in life.
In almost every case, gestational diabetes disappears on it's own after delivery, in which her blood glucose level return to normal about 6 weeks after childbirth. To be sure, the doctor may check the mother's blood sugar levels a few times after the birth, and some doctors recommend an oral glucose tolerance test 6-8 weeks after delivery to checks for diabetes.
Women who have had gestational diabetes have a 60% increased risk of developing type two diabetes later in life. By maintaining an ideal body weight, following a healthy diet and exercising, she will be able to reduce the risk of developing type 2 diabetes.
 


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last modified 30/11/11